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EDUCATION
  • 1997 BA, Biology in Society, Cornell University
  • 2001 MD, Medicine, Emory University School of Medicine
POSTDOCTORAL TRAINING
  • 07/01-06/02 Intern, Department of Medicine, University of Massachusetts Medical Center
  • 07/02-06/05 Resident, Department of Ophthalmology,
  • New York University/Manhattan Eye, Ear and Throat Hospital
  • 07/05-06/06 Clinical Fellow, Pediatric Ophthalmology, Medical University of South Carolina
CURRENT LICENSURE AND CERTIFICATION:
  • 2007 American Board of Ophthalmology
  • 2006 Massachusetts Board of Registration in Medicine
  • 2002 United States Medical Licensing Examination Completion
CURRENT HOSPITAL APPOINTMENTS
  • 11/2007-present Associate in Ophthalmology, Boston Children’s Hospital
  • 06/08-present Consultant in Ophthalmology, Brigham & Women’s Hospital
  • 07/08-present Consultant in Ophthalmology, Beth Israel Deaconess
  • 03/09-present Consultant in Ophthalmology, Massachusetts Eye and Ear Infirmary
  • 03/09-present Consultant in Ophthalmology, Massachusetts General Hospital
  • 03/13-present Consultant in Ophthalmology, South Shore Hospital
EMPLOYMENT
  • 2015- Present  Specialty Pediatric Eye Care, Beverly MA
  • 2007-Present Boston Children’s Hospital, Boston, MA
  • Specializing in pediatric ophthalmology and strabismus, I manage all clinical and surgical aspects of pediatric eye care, including pediatric cataract and glaucoma, amblyopia, strabismus, retinopathy of prematurity, ptosis, nasolacrimal duct obstructions and orbital/eye lesions.  In addition, I receive referrals from ophthalmologists for adult strabismus and referrals from pediatric ophthalmologists for the care of patients with Down syndrome and uveitis.
  • 2006-2007 Pediatric Ophthalmology and Strabismus Associates,Providence, RI
  • Specializing in pediatric ophthalmology and strabismus, I provided comprehensive pediatric eye care for the Providence area.   I also clinically and surgically managed adult strabismus, as well as adult cataract surgery at the Veterans Affairs hospital.
LEADERSHIP POSITIONS AND COMMITTEES
  • 2004-2005 Executive Chief Resident, Department of Ophthalmology, NYU
  • 2004-2005 Quality Assurance Committee, Manhattan Eye, Ear and Throat Hospital
  • 2007-2008 Surgical Research Committee, Boston Children’s Hospital
  • 2008-2009 Leadership Council, Boston Children’s Hospital
  • 2008-present Boston Children’s Hospital Teaching Academy member
  • 2007-2012 International Clinical Steering Committee, Boston Children’s Hospital
  • 2009-2011 Outcomes and Policy Committee, American Association for Pediatric Ophthalmology and Strabismus
  • 2011-2012 Research Committee, American Association for Pediatric Ophthalmology and Strabismus
  • 2011-2012 Performance Measures Workgroup, American Academy of Ophthalmology
  • 2011-present Physician’s Organization Congress, Boston Children’s Hospital
  • 2013-present Legislative Committee, American Association for Pediatric Ophthalmology and Strabismus
  • 2010-present National Universal Vision Screening for Young Children Coordinating Center Task Force, Prevent Blindness America
  • 2013 “Save Our Children’s Sight” Advocacy Day at the Massachusetts Statehouse, committee member and speaker
  • 2013-present Board of Health, Salem, MA
PROFESSIONAL ORGANIZATIONS, CURRENT MEMBERSHIP
  • 2005 American Academy of Ophthalmology, fellow
  • 2006  American Association for Pediatric Ophthalmology and Strabismus
  • 2008 Massachusetts Society of Eye Physicians and Surgeons, Member
  • 2009 New England Ophthalmological Society, member
  • 2012 American Academy of Pediatrics, member
CLINICAL SUPERVISORY AND TRAINING RESPONSIBLITIES
  • 2005-2006 Surgical and Clinical Instructor, Pediatric Ophthalmology Rotation,Medical University of South Carolina, Charleston, SC
  • 2006-2007 Surgical and Clinical Instructor: Rhode Island Hospital/Brown Department of Ophthalmology, Providence, RI
  • 2006-2007 Surgical Instructor, Veterans Affairs Medical Center/Brown Department of Ophthalmology, Providence, RI
  • 2007-present Surgical and Clinical Instructor, Boston Children’s Hospital, Boston, MA
SERVICE TO THE COMMUNITY
  • 2006-2011 Guatemala Surgical Mission Trip, 40-50 surgical cases per annual week trip, 7 trips
  • 2008-present National Down Syndrome Society Website Question and Answer
  • 2010   Boston Children’s Hospital Health and Science Blog “Should we change our eyeglass prescribing for children?”
  • 2011 Nepal Eye Hospital, education trip to work with Dr. Sabina Shrestha
  • 2013-present    Member of the Board of Health, Salem MA
  • 2014 Kiwi Magazine: National Children’s Eye Health and Safety Month
Academic Addendum RESEARCH CONTRIBUTIONS

Since being a summer research intern at Massachusetts Eye and Ear Infirmary in 1994, I have been involved in research endeavors, mainly clinical but also bench work.  I have had the opportunities to work with many principal investigators at different institutions including Emory, Tufts, NYU, multicenter trials like PEDIG (Pediatric Eye Disease Investigation Group) and eROP Cooperative Group (evaluating acute phase ROP), and working between Boston academic institutions over the past 7 years for collaborative research.  I have been the principal investigator on a number of studies including vision screening instrumentation, juvenile idiopathic arthritis related uveitis and Down Syndrome.  I have received grants from Prevent Blindness America to test vision screeners for children and from Lions Eye Research to conduct a fascinating study on instrument based measurement of the levels of Beta-amyloid in the lenses of people with Down syndrome compared to age matched controls.  This instrument could serve as a possible early non-invasive diagnostic test for Alzheimer’s disease.

  • Research Assistant, Prospective study on pharmacologic management of allergic conjunctivitis.
  • 2005-2006 MUSC/Storm Eye Institute (PI: Dr M. Edward Wilson)
  • Assistant Investigator, Retrospective study of primary intraocular lens implantation in children age 0 to 18
  • 2006-2007 Pediatric Eye Disease Investigation Group (PEDIG)
  • Assistant Investigator, “NLD2: a prospective trial on surgical management of persistent nasolacrimal duct obstruction”
  • 2008-present Boston Children’s Hospital and Boston Medical Center Collaboration (PI: Dr David Hunter)
  • Assistant Investigator, “Beta-Amyloid Lens Changes in Down Syndrome Patients as a non-invasive diagnostic of Alzheimer’s disease”
  • Lions Eye Research Funds
  • 2009-present Boston Children’s Hospital Teaching Academy
  • Principal Investigator, Ophthalmology Resident Surgical Education
  • 2009-present Boston Children’s Hospital
  • Principal Investigator, Down syndrome retrospective research including surgical management of nasolacrimal duct obstruction, relationship of cataract and refractive error, optic nerve anomalies and strabismus
  • 2010-present Boston Children’s Hospital/Boston Medical Center/New England College of Optometry Collaboration
  • Principal Investigator, Pediatric Vision Scanner and the “Spot” vision screener
  • Prevent Blindness America Grant
  • 2010-present eROP Cooperative Group
  • Assistant Investigator, Telemedicine Approaches to Evaluating Acute Phase ROP.
  • Multicenter NEI funded clinical trial
  • 2010-present, Boston Children’s Hospital and Massachusetts Eye and Ear Infirmary Collaboration
  • Principal Investigator, JIA uveitis outcomes in the age of TNF alpha inhibitors
  • 2013-present ARTISAN® Aphakia Lens for the Treatment of Aphakia in Children
  • Assistant Investigator, multicenter study under FDA-approved Investigational Device Exemption for the Artisan Aphakic lens.
TEACHING CONTRIBUTIONS

Teaching has been a focus of my early career and I have had the opportunity to be a part of the Boston Children’s Hospital Teaching Academy.  As part of this academy, I have been able to contribute to the improvement of the ophthalmology surgical training program.  These improvements include the development of a means for attending’s assessment of trainees, trainee self-assessment and other training tools such as a surgical video instructional library and participation in a new strabismus course and wet-lab.  In addition, I lecture the Harvard Medical Students 8 times a year as part of their core medicine block on ophthalmology which serves as the foundation of their knowledge for eye disease, diagnosis and care.  Over the past 9 years, I have given almost 90 lectures to medical and nurse practitioner students, residents, fellows, and other physician colleagues including neonatologists, anesthesiologists, primary care physicians, optometrists, and pediatricians.  The topics are largely pediatric ophthalmology related such as abusive head trauma, retinopathy of prematurity, pediatric cataract, vision screening, uveitis, and Down syndrome eye conditions.  I have had the opportunity to participate in national and international meetings including an international strabismus symposium in Nepal and the second world congress of pediatric ophthalmology and strabismus in Milan, Italy where I presented on the use of TNF-alpha inhibitors in JIA-related uveitis.

  • 2004 Surgical Instruction Course 2nd year ophthalmology residents,New York University
  • 2005 “Pediatric Ophthalmology”, Medical University of South Carolina Nurse Practitioner Students
  • 2006 OKAPS Review Series, Ophthalmology Residents, Medical University of South Carolina
  • 2006 “Non-Accidental Trauma”, Pediatrics Residents, Medical University of South Carolina
  • 2006 “Pediatric Cataract Extraction with intraocular lens implantation: visual acuity outcome when measured at age four years and older”, Podium Presentation, Annual Meeting of the American Academy of Pediatric Ophthalmology and Strabismus
  • 2006 “Pediatric Cataract Extraction with intraocular lens implantation: visual acuity outcome when measured at age four years and older”, Podium Presentation, Annual Meeting of the American Society of Cataract and Refractive Surgery
  • 2006 “Non-Accidental Trauma” and “Retinopathy of Prematurity” Lecture and Panelist, Anterior Segment Cataract Refractive Surgery/Medical University of South Carolina, Kiawah Island National Ophthalmology Meeting
  • 2006 “Retinopathy of Prematurity/” Grand Rounds, Lecture, Department of Pediatrics, Medical University of South Carolina
  • 2006 “Retinopathy of Prematurity” Grand Rounds, Lecture, Department of Pediatrics, Brown Medical School
  • 2007 “Angle Surgery” Glaucoma Conference, Panel Member, Department of Ophthalmology Brown Medical School, Providence RI
  • 2007 Topical Ketorolac Tromethamine and Retinopathy of Prematurity” Perinatology Conference, Women and Infant’s Hospital, Providence RI
  • 2007 “Pediatric ophthalmology” lecture, Brown Medical School Ophthalmology Residency
  • 2008 “OKAPS review”, lecture, Boston Children’s Hospital, Pediatric Ophthalmology Residents
  • 2008 “Non-Accidental Trauma” MEEI Ophthalmology Residents
  • 2008 “The Red Eye” Lecture, Frontiers in Pediatric Surgical Specialties, Massachusetts Medical Society
  • 2008 “Non-Accidental Pediatric Ophthalmologic Trauma”, Pediatric Grand Rounds, Joint Continuing Medical Education Committee, Lawrence General Memorial Hospital
  • 2009 “Strabismus, Pediatric Cataract & Retinopathy of Prematurity” Maine Optometric Society, Bar Harbour
  • 2009 “Vision Testing in Children” Lecture, Frontiers in Pediatric Surgical Specialties, Massachusetts Medical Society
  • 2009 “Non-accidental Trauma”, Lecture, Pediatric Healthcare Summit, CHB, Framingham Union Hospital
  • 2009 “Unique Aspects & Eye Care Management in Down Syndrome Patients” Lecture, Massachusetts Eye and Ear Infirmary Annual Meeting
  • 2009 “Retinopathy of Prematurity” Grand Rounds, Lecture, Department of Anesthesia, Boston Children’s Hospital
  • 2010 “Ocular Manifestation of Down Syndrome” Lecture, Longwood Medical Area Ophthalmology Conference
  • 2010 “Pediatric Strabismus” Pediatric Grand Rounds, Joint Continuing Medical Education Committee, Lawrence General Memorial Hospital
  • 2010 OKAPS review lecture, MEEI Ophthalmology Residents
  • 2011 OKAPS review lecture, MEEI Ophthalmology Residents
  • 2011 “Ophthalmology for the Primary Care Physician”, Department of Adolescent Medicine, Boston Children’s Hospital
  • 2011 “Vision Screening Instrumentation and Pediatric Ophthalmology”
  • 2011 “Current Concepts in Pediatric Uveitis”, Podium Presentation, American Academy of Optometry Annual Meeting
  • 2011 “International Strabismus Symposium” Nepal Eye Hospital, guest lecturer.  Supported by ORBIS. Kathmandu, Nepal
  • 2012 “Outcomes of JIA-associated uveitis: visual prognosis in the age of TNF-alpha inhibitor therapy”, Podium Presentation Free Paper World Congress Ophthalmology, Milan, Italy
  • 2012 “Screening Technology in Pediatric Ophthalmology”
  • Lions Eye Foundation
  • 2012 “Vision and Eye Issues in Children with Down Syndrome”, Boston Children’s Hospital, Down syndrome Program Speaker Series
  • 2012 “Inflammatory Eye Disease” Rheumatology Grand Rounds, Lecture, Boston Children’s Hospital
  • 2012 OKAPS review lecture, Boston Medical Center Ophthalmology Residents
  • 2012 “Why is an evidence base needed for changes in clinical care? Workshop
  • American Association for Pediatric Ophthalmology and Strabismus
  • 2013 “Infant Vision Screening” Learning Communities, PPOC practices
  • 2013 “Save our Children’s Sight” advocacy day at the Massachusetts Statehouse; invited speaker
  • 2013 “Ask the Pediatric and Adolescent Medicine Expert: Dermatology, Allergy and Ophthalmology”, invited speaker PRIMED East Conference
  • 2013 Surgical Instruction Course 2nd year ophthalmology residents,Boston University and Massachusetts Eye and Ear Infirmary
  • 2013 Pediatric Vision Screening, MEEI Ophthalmology Residents
  • 2014 Surgical Instruction Course 2nd year ophthalmology residents,Boston University and Massachusetts Eye and Ear Infirmary
  • 2014 “Advocacy Panel for Children’s Vision” Regional meeting of the American Association of Certified Orthoptists
  • 2008-present Pediatric Ophthalmology Seminars, Boston Children’s Hospital medical students, residents, fellows, 2 lectures/year
  • 2010-present “Core Medicine I” Harvard Medical School, 8 lectures/year
PUBLICATIONS

1.) Foster CS, Ledoux D. Types and Management of Ophthalmic Herpes Simplex Virus

Infections.  Herpes 1995; 2(1):  27-32.

2.) Dutt JE, Ledoux D, Baer H, Foster CS.  Collagen Abnormalities in Conjunctiva of Patients with Cicatricial Pemphigoid.  Cornea 1996; 15(6): 606-611.

3.) Fouladvand M, Ledoux DM, Barton JJS.  Ocular Myasthenia Gravis.  Comprehensive Ophthalmology Update 2005; 6(1): 25-36.

4.) Ledoux DM, Trivedi RH, Wilson ME, Payne JH.  Pediatric cataract extraction with intraocular lens implantation: Visual acuity outcome when measured at age four years and older. J AAPOS 2007; 11(3): 218-224.

5.) Ledoux DM. What’s your diagnosis?  Juvenile Xanthogranuloma of the iris.  J Pediatr Ophthalmol Strabismus. 2008; 45(2): 76.

6.) Pediatric Eye Disease Investigation Group.  Balloon Catheter Dilation and Nasolacrimal Duct Intubation for Treatment of Nasolacrimal Duct Obstruction after Failed Probing.  Arch Ophthalmol 2009; 127(5): 633-9.

7.) Mehendale RA, Dagi LR, Wu C, Ledoux D, Johnston S, Hunter DG. Superior rectus transposition and medial rectus recession for Duane syndrome and sixth nerve palsy.  Arch Ophthalmol. 2012; 130(2): 195-201.

8.) Ledoux DM, Johnston S, Walton DS. Angle surgery: goniotomy and trabeculotomy. In: Kahook M (ed.). Essentials of Glaucoma Surgery. Thorofare, NJ: SLACK Incorporated;2012:260-272.

9.) Schneier AJ, Heidary G, Ledoux DM.  Optic Nerve Appearance in Patients with Down Syndrome. J Pediatr Ophthalmol Strabismus. 2013; 50(1): 60.

10.) e-ROP Cooperative Group. Validity of a Telemedicine System for the Evaluation of Acute-Phase Retinopathy of Prematurity.  JAMA Ophthalmology 2014; June 26: E1-E7.

11.) e-ROP Cooperative Group. Telemedicine Approach to Evaluating Acute-phase Retinopathy of Prematurity: Study Design.  Ophthalmic Epidemiol. 2014 Aug 21(4): 256-67.